Botulinum toxin treatments (Neuromodulators) are popular non-surgical procedures that appeal to adults looking to attain a more youthful and relaxed appearance, and also to younger clients who want to prevent the formation of fine lines and wrinkles.

Botulinum toxin treatments South Africa

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Relax dynamic muscles and reduce unwanted lines associated with ageing.

Facial wrinkles are mainly caused by dynamic facial expressions, so halting them temporarily reduces or even removes facial wrinkles over time.

Dr Nerina Wilkinson has personally been using botulinum toxin injections to reduce her lines and wrinkles for the past 20 years. Her goal is not to create an expressionless face but to achieve a refreshed, relaxed look.

What are botulinum toxin injections?

Botulinum toxin treatments (Neuromodulators) are popular non-surgical procedures that appeal to adults looking to attain a more youthful and relaxed appearance, and also to younger clients who want to prevent the formation of fine lines and wrinkles.

Cosmetic Botulinum toxin therapy is classified as a schedule 4 medicine and is derived from a bacterium called Clostridium Botulinum, and acts as a neurotoxin targeting the nervous system, disrupting the nerve signalling processes that stimulate muscle contraction which stops muscle cells from contracting, allowing the muscle to relax and leave the skin smooth and rejuvenated.

Find out more about our approach to botulinum toxin injections (Neuromodulators), or book a consultation with Dr Nerina Wilkinson + Associates.

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Frequently asked questions about botulinum toxin treatments & muscle relaxing injections

Our approach to botulinum toxin injections

Dr Nerina Wilkinson has a set standard of individualised care and expertise which is reflected by the entire team. Our team of experts has a wealth of knowledge and continuously delivers outstanding results by using state of the art medical devices and products and sparing no expense to create a safe and luxurious environment where all your skincare concerns can be addressed. Each Botulinum toxin treatment is therefore completely bespoke and formulated around each individual’s concern and desired results.

We are passionate about educating our clients on safe, results-driven treatments and we design each client’s Skincare Treatment Plan individually to deliver optimal results.

Each Botulinum toxin injection procedure is completely bespoke and formulated around each individual’s concerns and desired results. Book an appointment to consult with our team of Medical Aesthetic experts.

How does botulinum toxin treat wrinkles and ageing?

1. Increases Skin Elasticity

Studies have shown that, unlike previously thought, muscle relaxing injections do more than simply paralyse facial muscles in the short term. Instead, the drug may be a leading cause for increased skin elasticity. Scientists have found that those who undergo Botulinum toxin injections may experience up to a 30% increase in the elasticity of their skin. What this means is that there’s more to the procedure than simply temporarily paralysing certain muscles. Specifically, elasticity in the skin helps to erase wrinkles over time, and studies have shown that even deep, ingrained wrinkles can be significantly reduced through the use of Muscle Relaxing Injections.

2. Fights Wrinkle Formation

It’s not just old wrinkles that botulinum toxin fights against. With increased skin elasticity, this treatment allows for the prevention of new wrinkles and may be responsible for the prevention of wrinkles over time in individuals who receive injections frequently. Muscle relaxing injections may affect both the skin and the muscles of patients, making it more difficult for wrinkles to form over time and protecting from the negative effects of ageing.

Who is the ideal candidate for botulinum toxin injections?

Botulinum toxin injections are suitable for those who want to rid the face of wrinkles, combat signs of ageing, treat excessive sweating, and even those who struggle with Bruxism (teeth grinding).

As with all cosmetic procedures, patient selection is probably the most important factor contributing to a successful outcome. The use of Botulinum toxin injections has successfully been used for the treatment of dynamic lines of the upper face (expression lines on the forehead and frown lines).

Great results can also be achieved in perioral rhytids (smoking lines), lip lengthening, “gummy smile”, drooping nasal tip, labiodental creases (drooping mouth corners), wrinkles around the eyes (crow’s feet), neckband and chin softening.

As with any medical aesthetic procedure, it is best to discuss your specific medical history and needs with your aesthetic doctor. Book an appointment to consult with our team of Medical Aesthetic Specialists.

How can botulinum toxin treat Bruxism (teeth grinding)?

Bruxism is a common and debilitating problem. Not only does it wear down, break and damage the teeth and fillings but regular and persistent grinding of the teeth can also result in jaw ache, headache, neck ache and earache. Bruxism usually happens subconsciously as we sleep. It is often a consequence of stress or anxiety.

There are two classifications of the problem:

Awake Bruxism: is characterised by involuntary clenching of the teeth and jaw bracing in reaction to certain stimuli. There is generally no tooth grinding with awake bruxism.

Sleep Bruxism: is characterised by automatic teeth grinding with rhythmic and sustained jaw muscle contractions

Commonly treated with uncomfortable mouth guards and muscular relaxation exercises – both techniques are generally found to be ineffective. Here at Dr Nerina Wilkinson + Associates, we can help with this problem by using precisely administered injections of Muscle Relaxing Injections to weaken the Masseter muscle, the muscle responsible for teeth grinding and clenching. The treatment can go a long way to help save your teeth and relieve headaches and pains caused by this troublesome condition.

How are botulinum toxin injections performed?

Once the Doctor has determined and confirmed your areas of concern by means of detailed consultation, they will proceed. Using a very fine needle, your doctor will inject a small amount (0.1ml –0.2ml) of botulinum toxin solution into the required areas of concern. The needles used are very fine so most people experience only mild discomfort.

Where does botulinum toxin come from?

Cosmetic Botulinum toxin (a schedule 4 medicine) is derived from a bacterium called Clostridium Botulinum commonly found in plants (such as), soil, and the intestinal tracts of mammals and fish.

How long do botulin toxin treatments take to perform?

Treatment time can vary between 30 – 45 minutes, depending on the area(s) treated.

How long do results from botulinum toxin injections last?

The full results of your treatment may take up to 14 days to take full effect. The results will last for an average of 3 – 4 months, depending on the condition of your skin, the area treated, amount of product injected, injection technique and lifestyle factors such as sun exposure and smoking.

Please follow these instructions in aid to achieve optimal results, and contact us to discuss your specific concerns.

Botulinum toxin injections: Before & After

The full results of your treatment may take up to 14 days to take full effect. The results will last for an average of 3 – 4 months, depending on the condition of your skin, the area treated, amount of product injected, injection technique and lifestyle factors such as sun exposure and smoking.

Please follow these instructions in aid to achieving optimal results:

Avoid make-up application for 2 hours at the injection sight to avoid contamination in the area.

For 4 hours – do not lie down or do strenuous exercise and similar activities, nor should you do anything that increases the blood flow to the injected area.

For 12 hours – avoid alcohol consumption

For 24 hours – do not rub or massage the treated areas as this could influence the effect of the product.

For 2 weeks – avoid direct sun exposure, UV light, freezing temperatures and saunas.

Tiny bumps or marks will go away within a few hours after your treatment, applying ice lightly to the area will offer relief.

Please note that no treatment can halt the ageing process completely, you will require top-up treatments if you want to maintain the effect, so please ask your Doctor when she would recommend rescheduling another appointment.

How long is the recovery period for botulinum toxin treatments?

The immediate recovery period for botulinum toxin injections is 48hrs, after which you must follow the aftercare instructions for up to 2 weeks to ensure successful results from your treatment.

How do I choose the best botulinum toxin treatment?

To see if this is the best skin science procedure for you, always start with a professional consultation with a qualified and experienced skincare professional for an in-depth analysis of your facial features and to reach a good understanding of your skincare concerns and goals.

Dr. Nerina Wilkinson + Associates’ unique and comprehensive skin science consultation is available for you to discuss and analyse your concerns and goals and for Dr Nerina Wilkinson (together with her team of specialists) to provide bespoke advice.

Schedule your aesthetic couture consultation today!

What do botulinum toxin treatments cost in South Africa?

The cost of treatment depends on your face shape, concerns, personal goals, how much product is required, and the treatment(s) required. You will be provided with an estimate after your initial Doctors consultation. We are unable to provide you with an exact cost/quotation pre-treatment as we place our focus on achieving your desired results.

Your personalised journey will begin with an in-depth consultation where you will be provided with an Aesthetic Couture plan which outlines recommended procedures and the exact steps required to achieve the results you desire; we quote on the steps required to achieve this outcome, not simply on the amount of product required.

Start your aesthetic couture consultation and contact us to book.

Are botulinum toxin treatments safe?

Botulinum toxin injections are currently among the safest treatment methods available. 99% of treatments are entirely free of adverse effects when administered correctly. If side effects ever occur, they are generally mild and temporary. No long-term effects of botulinum toxin have been reported after twenty years of clinical experience. However, women who are pregnant or nursing should take caution and avoid muscle relaxing injections (botulinum toxin) during this period.

What are the possible risks and complications associated with botulinum toxin injections?

Your health and lifestyle should always be assessed in conjunction with your expectations before the Botulinum toxin treatment.

Adverse effects are unlikely but there are common side effects, risks and complications that can be associated with a Botulinum toxin treatment which a qualified Doctor will be able to assess and advise you on prior to treatment.

Botulinum toxin injections side effects

Dr Nerina Wilkinson + Associates can provide more insight into any additional side effects associated with muscle relaxing injections, and address any concerns you may have regarding eyelid surgery. Contact us to find out more.

Botulinum toxin injections Contra-indications

It is advised that you do not receive Botulinum toxin Injections should you be
affected by any of these medical conditions:

  • Cancer or metastatic disease
  • An open wound with infection
  • A low platelet count
  • Pregnancy
  • Autoimmune disease.
  • Diabetes
  • Poor wound healing or Keloidalis
  • Patients on anticoagulants
  • Active skin cancer

What is the difference between botulinum toxin injections and dermal fillers?

Botulinum toxin is a neuromodulator and botulinum toxin injections cause paralysis of the muscle by disrupting the nerve signalling causing the muscle to relax and the surface of the skin to smooth out. Dermal Fillers on the other hand are injections that restore volume and fill the skin to create a youthful appearance. Both treatments are temporary and are used together to create your desired aesthetic result.

Where can I find botulinum toxin treatments in Cape Town?

Botulinum toxin treatments are usually performed in private cosmetic clinics and other medical clinics that have a focus on skin science treatments.

Dr Nerina Wilkinson + Associates is a private, high end, and luxurious clinic located in the prestigious V & A Waterfront in Cape Town where Dr Wilkinson founded the House of Aesthetic Couture and Skin Science.

Learn more about our aesthetic couture consultation or contact us.


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The Aesthetic Couture Team

Dr Narina Wilkinson and team

About Dr Nerina Wilkinson + Associates

We pride ourselves on affording our patients the best service through their journey with us. Whether you are having a skin treatment with one of our skin care experts, aesthetic medical treatments or having cosmetic surgery, the team at Dr Nerina Wilkinson and Associates will be there for you, every step of the way.

Skin Science & Aesthetic Couture

Our Team has pioneered highly effective, science-driven techniques. Integrating the most cutting edge technologies, state of the art equipment and sound scientific research. We design game-changing protocols that redefine skin care, aesthetic medicine, and plastic surgery.

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Our Patients'


An excellent team who will tailor make a skin treatment plan for you. They are all extremely knowledgeable and professional and use all the latest anti aging technologies and treatments. Amazing attention to detail from the beautiful space to the follow up care kits and check in emails from the therapists. Really a five star experience.

J Anastasopoulos

I have been with Dr Nerina Wilkinson and her team since 2021 and the level of professionalism is unmatched. So are the treatments, they truly have a solution for almost every skin or aesthetic concern. Could not love them more!

A Davids

My experience at Dr Nerina Wilkinson has been nothing but significant! I feel that for the first time, I understand my skin. Thanks to the lovely Louné, that has created a specific skin plan and routine for me. I am 39 years old and struggle with Pigmentation and Skin ageing. Our goal is to make my skin look as fresh, natural and glowing as possible. I have the utmost confidence in Louné to reach my goal. I started my journey with them in January 2023 and my results after doing a Meline Peel are already proofs that I am on the best plan. I am excited and confident to reach my goal and cannot wait for my next appointment! I would definitely recommend their professional opinions.

T Strauss

This is my honest review. I was very sceptical when I made an appointment at Dr Nerina Wilkinson and Associates, I thought like every other place that has influencers going there that it wouldn’t hold up to its reputation. I was wrong! Very wrong. Dr Cindy Kerbel was incredible, she took her time to explain not only my skin but all the available options for my skin. She has such a warm and kind energy. You immediately feel cared for. Honestly you won’t regret going here. I cannot wait for my next appointment. Thank you!

J Bentel

To avoid prolixity, you know your people are undeniably unbeatable when arguments relating to your age arise in conversations (read online dating apps). Despite clinging to the ‘wrong side’ of 30, I’ve made peace with those who assume I am still at varsity. Between Marisa and Bernice (with a shout-out to Natalie (as well as the rest of the team)) my skin and jawline (and the rest) have never looked more delicious. And when the Finance and Facility Manager is also a vibe, you know you’ve found a gem of a team! In short, I’m addicted (hypothetically, of course) to the needles (in a healthy wholesome way, naturally) and am never looking back (in particular at old Facebook photos when youth was allegedly in my favour). Thanks for keeping my aesthetic *ish together.

A Wright

I am so glad that, at the age of 30, I finally decided to come here! Such a warm and professional atmosphere, and Chantel made me feel so comfortable and excited for this journey. After my in-depth skin analysis and consultation, I was very happy with the first treatment, and for what has been planned ahead. Thank you!

F Badenhorst

I’ve gone for 2 appointments so far and 1. the service is incredible, such friendly and professional staff, 2. I had my skin analysed and then also went for a skin treatment and my skin is thanking me for it. I cannot wait to go back for more treatments. Highly recommend.

N Jacobs

I recently went to Dr Nerina Wilkinson + Associates to help me with my Rosacea. Walking into their beautiful, tranquil space is transforming alone. I love that they have a signature scent, which smells amazing. Each member of the team is passionate about what they do and incredibly knowledgeable, whilst always staying informed with the latest in skincare, technology etc.

B Georgiades

During my extended stay in Cape Town, I (Black American female), visited Dr. Nerina Wilkinson + Associates to maintain my skincare regimen while abroad. I was fortunate to work with my skincare specialist to develop a tailored skincare treatment. Not only did I receive great service, but she also provided detailed insight into the current state of my skin and offered additional recommendations for overall skin health. Chantel was excellent, demonstrating both kindness and informative expertise, and the facility was beautiful. And overall, I did see improvement in my skin’s texture and evenness, but I still have a ways to go.

C Okpara

Growing up I did not pay much attention to looking after my skin properly, but after starting my journey with Dr Nerina Wilkinson + Associates it has become one of the most important steps in my daily routine and I am loving it thanks to their delightful, informed and supportive team. I have always struggled with broken capillaries and dehydration, but have never known how to go about treating it and preventing further damage in the future. I had my first IPL session last week and I am absolutely shocked by the amazing results thus far. I was very wary about leaving my home during the COVID19 pandemic, but the team at Dr Nerina Wilkinson + Associates not only made me feel incredibly safe but I was also treated like a true queen during my session. After the treatment I received a ‘lucky packet’ of aftercare products and Bernice was there at my every beck and call (as I had many questions which were answered in such a timely and gracious manner). She also recommended products that have made my face feel softer and more youthful than ever before and I can already start seeing/feeling a difference. I am so grateful to the incredible team and I look forward to a future of beautiful care and loving myself in my own skin.

K Fourie

Growing up in the US, I went to dermatologist after dermatologist, and each one said the same three things: I have acne, it’s genetic, and it could be a lot worse. When I moved to Cape Town a few years ago, I heard from a friend that I needed to go see the women at the Nerina Wilkinson skin clinic, so I made an appointment – but I didn’t expect anything different. I left their office after my first appointment with Kim and I had some real hope for my skin to improve. She changed my home care, worked out a long term plan for me, and even gave me her personal cell number so I could message her if things weren’t working. It’s been over two years now and I have never been so happy with my skin. Kim and the other women at the skin clinic form the kindest and most caring team of professionals and I can’t thank them enough. From scalp PRP treatments for thinning hair, to lasers and peels for my rosacea, I’ve tried my fair share of treatments at this office and every single one of them has been worth it – I can honestly say these women have helped me feel like the best version of myself!

A Newell

“I have spent too much money over the past 10 years in hope to sort out my pigmentation and skin texture. Visited many (un)professionals and bought the most mediocre skincare. I heard about Dr Nerina via a friend. My last hope and the best decision I made. I was introduced to the Me Line peel and their skincare…this is now my go to as my skin has never looked this good and healthy ever. Extremely professional team, Bianca was my therapist. If you are looking for skin changing results and are serious about proper skincare, you should visit them. It’s worth all the money you will spend. An investment worth it…”


“Thank you to the wonderful ladies at your skin clinic. I have always suffered from problem skin. They have over the last few months advised me on the correct skincare and through their dedicated treatments I am now proud to show my skin without wearing too much makeup.”

Skincare Treatments

“Every day I look in the mirror, I can’t believe that this new skin in mine! I reached a point in my life where I thought that I would have to live with the consequences of the severe sun damage I have caused myself through years of surfing. Not only have you given me new skin Nerina, you have actually given me a new life.”

L.S, CO2 Laser Resurfacing Treatment

“My grateful thanks to you all for everything you do for me, and I mean that from the heart of my bottom!”

Skin Science Treatments

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