PRX Plus Peel in South Africa
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Achieve brighter, smoother and rejuvenated skin with our PRX Plus Peel
Experience advanced skin biorevitalisation that stimulates collagen, reduces pigmentation and refines texture, all with zero downtime and no needles required.
What is the PRX Plus Peel?
The PRX Plus Peel is a non-invasive skin biorevitaliser that delivers deep dermal regeneration without peeling or downtime.
Using a unique massage application technique, it stimulates fibroblast activity and neocollagenesis to improve skin texture, brightness and hydration. Ideal for fine lines, pigmentation, sun damage and post-acne scarring, with results visible from the first session.
Learn about our approach, how treatments are performed, and book your consultation.
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Frequently Asked Questions About PRX Plus Peels
Our approach to PRX Plus Peels
At Dr Nerina Wilkinson + Associates, we believe exceptional skin results begin with truly understanding your skin.
Every PRX Plus treatment starts with a detailed consultation and computerised VISIA Skin Analysis, allowing your Skincare Specialist to objectively assess and map your skin before designing a protocol tailored to your specific concerns.
From your first session through to aftercare guidance, each step is thoughtfully structured to stimulate lasting skin renewal, with your comfort and results at the forefront.
Schedule your consultation to find out how the PRX Plus Chemical Peel can transform your skin.
What ingredients are used in PRX Plus Peels?
The PRX Plus formulation combines five active ingredients, each selected for a specific role in skin renewal.
- Homocysteic Acid: a sulphur-containing amino acid that accelerates skin turnover and supports collagen stimulation with minimal downtime
- Ammonium Trichloracetate: a biorevitalisation and exfoliating agent that stimulates fibroblasts in the dermis to improve skin tightness, texture and tone without disrupting the skin’s barrier
- Phytic Acid: a gentle antioxidant AHA that inhibits pigmentation and brightens the complexion
- Citric Acid: an AHA that enhances cell turnover and refines skin tone and texture
- Tartaric Acid: an antioxidant AHA that supports pore reduction and cellular renewal
Together, these ingredients deliver meaningful, visible results with minimal downtime. Book your consultation to find out how the PRX Plus Chemical Peel can work for your skin.
Who is the ideal candidate for PRX Plus Peels
The PRX Plus Chemical Peel is suited to individuals looking to address visible signs of ageing, pigmentation or skin damage, without the downtime associated with more intensive procedures.
These symptoms or experiences may be a sign that you are a good candidate:
- Fine lines and wrinkles, skin laxity or a loss of elasticity that you would like to address non-invasively.
- Uneven pigmentation, sun damage or photoageing and are seeking a brighter, more even complexion.
- Deal with post-acne scarring, enlarged pores or recurring breakouts that have affected your skin’s texture and tone.
- Dull, dehydrated skin and are looking to restore radiance and hydration through a course of targeted treatments.
It is also important that you are in good general health with no active facial rashes, open wounds, dermatitis or other contraindications to treatment.
A thorough consultation with your Skincare Specialist will determine the most suitable protocol for your skin type, concerns and goals. Book your consultation to find out if the PRX Plus Chemical Peel is right for you.
Which areas can PRX Plus treat?
PRX Plus can be applied to the face, neck and chest to target concerns such as fine lines, pigmentation, uneven texture, and post-acne scarring in these areas.
Your Skincare Specialist will confirm the most appropriate treatment zones during your consultation based on your specific concerns and goals.
Book your consultation to discuss your treatment areas.
How is a PRX Plus Peel performed?
A PRX Plus treatment is a straightforward, non-invasive procedure performed in a clinical setting.
First, the skin is thoroughly cleansed to remove any surface impurities and prepare it for treatment. Next, your Skincare Specialist applies the PRX Plus formula to the desired treatment area using a specialised massage technique, which is central to how the active ingredients penetrate the dermis, stimulating collagen production and cellular renewal without disrupting the skin barrier or causing visible peeling.
Some mild tingling or warmth may be experienced during this step.
Finally, a moisturiser and SPF are applied to protect and support the skin immediately post-treatment.
Ready to experience it for yourself? Book your PRX Plus treatment today.
What are the benefits of PRX Plus Peels?
PRX Plus delivers a range of skin benefits without the downtime or discomfort associated with more intensive procedures.
- No needles, no downtime: PRX Plus stimulates deep dermal renewal through a massage application technique, with no disruption to the skin’s surface
- Improved skin texture and tone: progressive improvement in surface irregularities, uneven skin tone and overall skin quality across a course of treatments
- Collagen stimulation: fibroblast activity is triggered deep within the dermis, supporting skin firmness and elasticity over time
- Pigmentation and dark spot reduction: active ingredients work to inhibit melanin production and brighten the complexion
- Hydration and radiance: deep hydration is restored, leaving skin with a natural glow and a smoother, more refreshed appearance
- Reduced appearance of fine lines and enlarged pores: cellular renewal and neocollagenesis progressively refine and tighten the skin
- Suitable for a wide range of skin types and concerns: from sun damage and post-acne scarring to mild laxity and early signs of ageing
- Includes a bespoke aftercare pack: each session comes with product minis tailored to support your skin’s recovery post-treatment
Contact us to learn more about the benefits of a PRX peel and book your consultation to get started.
How does PRX Plus differ from traditional chemical peels?
Unlike traditional chemical peels, PRX Plus delivers deep dermal stimulation without visible peeling or surface trauma to the outer layer of the skin.
Traditional chemical peels typically work by removing the epidermis to trigger renewal, which often results in significant downtime.
PRX Plus uses a unique formulation to stimulate collagen production and fibroblast activity within the dermis while preserving the skin barrier, making it suitable for a wider range of skin types and concerns.
How long does a PRX Plus Peel take?
Each PRX Plus session takes between 30 and 45 minutes, making it a practical treatment option that fits easily into a busy schedule.
Book your consultation today to learn more.
How many PRX Plus Peels are required to see results?
A course of 4 PRX Plus treatments, spaced 2 weeks apart, is recommended for optimal results.
This allows the active ingredients to progressively stimulate collagen production, improve skin texture and tone, and address concerns such as pigmentation, fine lines and post-acne scarring over time.
Your Skincare Specialist will assess your skin during your initial consultation and may adjust the number of sessions based on your specific skin concerns and goals.
Book your consultation to discuss your personalised treatment plan.
What is the recovery period of PRX Plus Peel?
PRX Plus requires no formal downtime, allowing most patients to return to their daily activities following their session.
Some redness and a mild sunburned sensation can be expected for up to 24 hours post-treatment, and skin tightness, dryness or flaking may be experienced in the days that follow.
Your Skincare Specialist will provide a bespoke aftercare pack and detailed guidance on caring for your skin in the days following your treatment, including recommendations for sun protection.
Book your consultation to find out what to expect before, during and after your PRX Plus Chemical Peel.
How long do results from PRX Plus Peels last?
The longevity of PRX Plus results will vary from patient to patient, depending on factors such as skin type, the severity of the concern being treated and adherence to post-treatment home care.
Completing the recommended course of 4 treatments provides the strongest foundation for lasting improvement in skin quality, texture and tone. To sustain and build on these results, your Skincare Specialist will outline a personalised maintenance plan and skincare regimen suited to your skin’s ongoing needs.
Book your consultation to discuss your long-term skin goals and how PRX Plus can help you achieve them.
How much does a PRX Plus Peel cost in South Africa?
Medical-grade chemical peels at aesthetic clinics in South Africa typically range from R1 500 to R6 000 per session, depending on the treatment area, the technology used and the level of clinical expertise involved.
At Dr Nerina Wilkinson + Associates, PRX Plus Full Face treatments start from R2 200, and Full Face and Neck from R2 400 per session. Each treatment includes a bespoke aftercare product pack to support your skin after the session.
Patients purchasing a course of 3 or more treatments will receive a discount on the total price.
Book your consultation to discuss your treatment plan and receive a personalised quote.
Is PRX Plus Treatment safe?
When performed by a qualified Skincare Specialist in a medical environment, PRX Plus is a safe, non-invasive treatment with a well-established clinical profile.
The formulation works by stimulating dermal regeneration from within, using a combination of active acids and biorevitalisation ingredients that support the skin’s natural renewal processes without disrupting the skin barrier or causing surface trauma.
Rare adverse effects such as post-inflammatory hyperpigmentation, sterile pustules, severe skin peeling or prolonged erythema have been reported, though most patients do not experience these complications.
It is important to disclose any relevant medical history, medications and known allergies to your Skincare Specialist prior to treatment, as certain conditions, including pregnancy, immunosuppression, active facial rashes and dermatitis, are contraindications.
All PRX Plus treatments at Dr Nerina Wilkinson + Associates are performed by qualified Skincare Specialists following carefully structured protocols to ensure your comfort and safety throughout.
Contact us to discuss the safety and suitability of PRX Plus for your skin during your consultation.
What are the possible risks and complications associated with PRX Plus Treatments?
When performed by a qualified Skincare Specialist in a clean, medical environment, PRX Plus treatments are well-tolerated by most patients and carry a low risk of adverse effects. However, as with any skin treatment, there are potential risks and considerations to discuss during your consultation.
PRX Plus Treatment: Side Effects, Risks & Complications
- Post-treatment redness: A sunburned sensation and visible redness can be expected for up to 24 hours following treatment, typically resolving without intervention.
- Skin tightness and swelling: Mild tightness may be experienced in the days following treatment due to temporary swelling.
- Skin flaking and dryness: Some peeling, dryness and increased skin sensitivity have been reported in the days following treatment as the skin renews.
- Post-inflammatory hyperpigmentation: In rare cases, darker skin tones may experience temporary pigmentation changes following treatment.
- Sterile pustules: A rare inflammatory response that resolves without medical intervention in most cases.
- Prolonged photosensitisation and erythema: In rare instances, increased skin sensitivity to light and persistent redness have been reported for up to 14 days post-treatment.
Contraindications for PRX Plus Treatment
- Ingredient allergies: Known sensitivity or allergy to any of the active ingredients in the PRX Plus formulation.
- Active facial rashes and open wounds: Any broken skin or active infection in the treatment area.
- Dermatitis: Including eczema, psoriasis and seborrhoea.
- Cold sores or fever blisters: Active or recurring herpes simplex in the treatment area.
- Weakened immune system or serious illness: Including patients who are immunosuppressed or currently undergoing chemotherapy.
- Pregnancy: PRX Plus is not recommended during pregnancy.
Contact us to discuss the suitability of PRX Plus for your skin and any concerns you may have prior to treatment.
PRX Plus Treatment: Before and After
Preparing correctly for your PRX Plus Chemical Peel and following the recommended aftercare guidelines are key to achieving the best possible results from each session.
Below, we outline what to do before, during and after your treatment.
Before your PRX Plus Treatment
- Avoid retinols and AHAs for 15 days before your appointment to minimise the risk of skin sensitivity.
- Refrain from hair removal treatments, including waxing, electrolysis, laser hair removal and hair removal creams for 7 days before your session.
- Avoid any skin treatments that may irritate your skin for two weeks leading up to your appointment.
- Refrain from any aesthetic procedures, including Botulinum Toxin, facial fillers and threads, for two weeks before your treatment.
- Disclose all current medications and any known ingredient allergies to your Skincare Specialist before treatment.
- If you are preparing for a special event, schedule your course of treatments well in advance to allow sufficient time between sessions and recovery.
Day of your PRX Plus Treatment
- Arrive with a clean face, free of makeup and skincare products where possible.
- New patients will be required to complete a short medical questionnaire to assist your Skincare Specialist in selecting the most appropriate protocol.
- Your Skincare Specialist will require access to your face, neck and shoulders, so a robe will be provided before your session.
- Your treatment will include a skin cleanse, application of the prescribed PRX Plus peel, moisturiser, and SPF, and will be completed within 30 to 45 minutes.
What to do after your PRX Plus Treatment
- Apply SPF 50 twice daily to protect the skin and support your results.
- Limit sun exposure for 2 to 5 days following your treatment.
- Avoid vigorous exercise for 2 days post-treatment.
- Avoid steaming-hot showers, saunas, jacuzzis and steam rooms for the first three days following your session.
- Avoid facial waxing for 14 days post-treatment.
- Do not pick, rub or scratch any flaking skin.
- Avoid anti-inflammatories and icing the treated area, as the inflammatory response encourages the release of growth factors within the skin.
- Follow the personalised aftercare regimen provided by your Skincare Specialist to support your skin’s recovery between sessions.
Contact your Skincare Specialist if you experience any unexpected reactions or have questions following your treatment.
Where are PRX Plus Peels performed in Cape Town?
PRX Plus Chemical Peel treatments are performed at the Dr Nerina Wilkinson + Associates skin clinic, located at the prestigious V&A Waterfront in Cape Town.
Our physician-led team of Skincare Specialists delivers every treatment within a private, medically equipped environment, where clinical precision and personalised care are the standard at every visit.
From your initial VISIA Skin Analysis through to your post-treatment aftercare, each step of your PRX Plus journey is carefully managed to ensure your comfort, safety and results.
Book your consultation and take the first step toward healthier, more radiant skin.
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At Dr Nerina Wilkinson + Associates, personalised care and clinical expertise define every patient experience. From advanced skincare treatments to surgical solutions, our dedicated team supports you with precision and compassion at every stage of your journey.
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Our all-female team believes radiant skin begins with confidence and expert guidance. Driven by a commitment to innovation and real results, we offer a carefully curated selection of premium skin protocols, including 3D Medical Skin Needling, FORMA™ Hydralyft , and the 3D MD PRP facial.

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PRX Plus Peel Journey
Our Skincare Specialists at our clinic in the V&A Waterfront are here to guide you through every step of your PRX Plus Chemical Peel Treatment journey.
We combine advanced biorevitalisation technology with medical-grade ingredients and a personalised approach to create a custom plan for your skin’s unique needs, helping you achieve lasting firmness and a radiant glow.
Contact us today to find out how the PRX Plus Chemical Peel can restore elasticity, clarity and confidence to your skin.



