Mesotherapy and Skin Boosters are non-surgical, skin rejuvenating treatments. Tiny droplets of active ingredients, including hydrating Hyaluronic Acid and skin rejuvenating vitamins, are delivered into the middle layer of the skin.

Mesotherapy Treatments & Skin Boosters South Africa

Mesotherapy provides targeted and customised skin rejuvenation for a range of skin concerns.

Mesotherapy and Skin Boosters are non-surgical, skin rejuvenating treatments. Tiny droplets of active ingredients, including hydrating Hyaluronic Acid and skin rejuvenating vitamins, are delivered into the middle layer of the skin.

This technique directly delivers active ingredients into the area most needed and is tailored to directly target specific skin concerns. If you notice aged, sagging skin with poor overall texture – mesotherapy might be for you.

What is Mesotherapy & what are Skin Boosters?

Mesotherapy is a popular, minimally invasive technique using small injections to introduce active ingredients into the superficial layers of the skin, in order to stimulate, feed and regenerate the skin without the damage or trauma that most surgical and even other aesthetic cosmetic procedures require to activate skin rejuvenation.

Skin Boosters are deeper injections of bespoke actives, administered by a Medical Aesthetic Doctor. Skin Boosters provide similar results to Mesotherapy but last longer with fewer treatments required to see optimal results.

Find out more about our approach to mesotherapy treatments and skin boosters, or book a consultation with Dr Nerina Wilkinson + Associates.

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Frequently asked questions about Mesotherapy treatments & Skin Boosters

Our approach to Mesotherapy treatments & Skin Boosters

Dr Nerina Wilkinson has a set standard of individualised care and expertise which is reflected by the entire team. Our team of experts has a wealth of knowledge and continuously delivers outstanding results by using state of the art medical devices and products, sparing no expense to create a safe and luxurious environment where all your skincare concerns can be addressed. Each Mesotherapy and Skin Booster treatment is therefore completely bespoke and formulated around each individual’s concern and desired results.

We are passionate about educating our clients on safe, results-driven treatments and we therefore design each client’s Skincare Treatment Plan individually to deliver optimal results. To achieve this, we start with a computerised VISIA Skin Analysis that objectively measures and maps your skin followed by a detailed consultation with your Skincare Specialist during which specific concerns are highlighted and discussed.

Who is the ideal candidate for Mesotherapy treatments & Skin Boosters

Mesotherapy is ideal for those wanting a more even complexion with an instantly bright and healthy glow.

While treatments are customised to individual skin concerns, the most popular indication for Mesotherapy is ageing; the skin will appear smoother, softer and more youthful after each Mesotherapy session.

Other specific skin symptoms that can be treated with the use of Skin Boosters or Mesotherapy treatments, including:

  • Fine lines and wrinkles 
  • Dry/dehydrated skin 
  • Dull, lifeless skin 
  • Skin sagging 
  • Poor texture 
  • Ageing

As with any medical aesthetics procedure, it is best to discuss your specific medical history and needs with your doctor. Book an appointment to consult with one of our Aesthetic Doctors.

How are Mesotherapy treatments performed?

Should this be your first treatment at the Skin Clinic, you will be required to complete a short medical questionnaire to help guide your Skincare Specialist in selecting the most suitable protocol for you. Your Skincare Specialist will require access to your face, neck and shoulders, therefore requiring you to get changed into a robe prior to the treatment.

A Mesotherapy skin treatment will include: 

  • Cleansing 
  • Application of a bespoke skin serum/solution 
  • Use of micro mesotherapy needles to enhance penetration of the active ingredients 
  • Skin Tonic & SPF application 

How long do Mesotherapy treatments take to perform?

Treatment time will vary according to the area being treated but will usually last about 30 – 45 minutes. 

We recommend a monthly treatment to maintain healthy, glowing skin and to combat the signs of aging. For best results, we recommend combining this with other treatments such as Lumecca Intense Pulsed Light and 3D Micro-Needling.

How long do results from Mesotherapy treatments & Skin Boosters last?

Mesotherapy will leave your skin looking radiant and revitalised. Improved hydration levels in the skin will be noted from day 2 and the skin will appear plumper and smoother. The formation and maturation of the new collagen will take up to 90 days post-treatment. This means that the best results can be expected about 3 months after the treatments, however, most patients start to see excellent results once a course has been completed.

Please contact us to discuss your specific concerns.

Mesotherapy & Skin Boosters: Before and After

Before Mesotherapy treatments & skin boosters

Before undergoing a Mesotherapy treatment, you are required to:

  • Avoid any strong at-home facial treatments and/or exfoliation treatments the week prior to your appointment.
  • Avoid sun exposure (including tanning) for five days prior to your treatment.
  • If prone to fever blisters it is important to inform your Skincare Specialists as a fever blister medication needs to be started 3 days prior to the treatment to prevent an outbreak post-treatment.
  • Know the skincare products you are using at home, bring a list, as having these details will assist your Skincare Specialist to make suitable product recommendations.
  • Advise your Skincare Specialist regarding any medications, medical conditions, and/or past skin conditions; even over-the-counter medications can affect your skin, so it is good for us to know what may be contributing to your concerns, as well as how your skin reacts to certain products.
  • Know the skincare products you are using at home, bring a list, as having these details will assist your Skincare Specialist to make suitable product recommendations.
  • Advise your Skincare Specialist regarding any medications, medical conditions, and/or past skin conditions; even over-the-counter medications can affect your skin, so it is good for us to know what may be contributing to your concerns, as well as how your skin reacts to certain products.
  • Should you be preparing your skin for a big event and you have never had a skincare treatment before and therefore don’t know how your skin will respond, it is recommended that you schedule an appointment six weeks before your big event with a follow-up appointment closer to the event date. This way you have time to address any negative skin reactions and get the maximum results from your treatment(s).
  • Be prepared to discuss your skin concerns and goals. Your Skincare Specialist is a licensed expert who will provide you with a detailed plan to best achieve your specific goals.
  • We advise against any aesthetic procedures (including Botulinum Toxin, Facial Fillers and Threads) 2 weeks prior to and 2 weeks after any minimally invasive skin care treatment.

After Mesotherapy treatments or Skin Boosters

The treatment area may appear flushed for 1 – 2 hours post-treatment. You may experience a tight, dry sensation for the first 48 hours afterwards. This treatment is known as a “no downtime” procedure however as a result of the micro-injections, minimal swelling and bruising could be expected for a day or two post-treatment.

Your Skincare Specialist will advise on a suitable skincare regime to support results (treatment includes a bespoke aftercare pack consisting of relevant product mini’s to aid the recovery of your skin post-treatment)

  • An SPF 50 sun protectant should be applied daily.
  • Avoid facial waxing for 7 days post-treatment.
  • Limit sun exposure for 2 – 7 days post-treatment.
  • Avoid exercise for 24 hours post-treatment.

How long is the recovery period for Mesotherapy or Skin Boosters?

Minimal to no downtime – no exercise for 24 hours and some minor swelling and bruising may occur for 1-2 days post procedure.

How do I choose the best Mesotherapy procedure for me?

To see if this is the best skin science procedure for you, always start with a professional consultation with a qualified and experienced skincare professional for an in-depth analysis of your facial features and to reach a good understanding of your skincare concerns and goals.

Dr. Nerina Wilkinson + Associates’s unique and comprehensive skin science consultation is available for you to discuss and analyse your concerns and goals and for Dr. Nerina Wilkinson (together with her team of specialists) to provide bespoke advice.

Contact us to schedule your skin science consultation today!

What does Mesotherapy cost in South Africa?

At Dr. Nerina Wilkinson + Associates, our cosmetic mesotherapy treatment pricing is as follows:


  • Mesotherapy Face: R 2 750
  • Mesotherapy Face &  Neck: R 3 150

Consists of pre-mixed cocktails to target either firming and tightening, photoaging, and sun damage or depigmentation.

The cost includes a bespoke aftercare pack consisting of relevant product minis to aid the recovery of your skin post-treatment.

Start your skin science consultation journey and contact us to book.

Is Mesotherapy safe?

No procedure is risk-free, however, when a qualified Skincare Specialist performs Mesotherapy in a sterile medical environment the risks diminish significantly. Mesotherapy and Skin Boosters can be safely performed on all Fitzpatrick skin types.

Mesotherapy & Skin Booster Treatments: Possible risks

When a qualified Skincare Specialist performs Mesotherapy in a sterile medical environment the risks diminish significantly.

If prone to fever blisters it is possible to experience a fever blister break out after Mesotherapy due to inflammation in the skin. It is important to inform your Skincare Specialists if you have a history of fever blisters, as fever blister medication needs to be started 3 days prior to the treatment to prevent viral activation.

Because Mesotherapy and Skin Boosters make use of a needle there is the possibility of bruising, although this is unlikely.

Mesotherapy & Skin Booster Treatments: Possible side effects

Dr. Nerina Wilkinson + Associates can provide more insight into any additional side effects, and address any concerns you may have regarding Mesotherapy and SKin Booster procedures. Contact us to find out more.

Where are Mesotherapy treatments performed in Cape Town?

Mesotherapy treatments are usually performed in private cosmetic clinics and other medical clinics that have a focus on skin science treatments.

Dr Nerina Wilkinson + Associates is a private, high end, luxurious clinic located in the prestigious V & A Waterfront in Cape Town where Dr Wilkinson founded the House of Aesthetic Couture and Skin Science.

Learn more about our skin science consultation journey or contact us.


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The Skin Science Team

cosmetic facial procedure

Skin  Science & Aesthetic Couture

Our Innovative, personalized physician-led team have pioneered highly effective, science-driven techniques. Integrating the most cutting edge technologies, state of the art equipment and sound scientific research.

About Dr Nerina Wilkinson + Associates

When you choose us, you can be confident that during your treatments, you are receiving the highest quality service. Our environment is luxury but more important we are led by our distinguished group of doctors, so you can be assured of your safety at all times.

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Our Patients'


An excellent team who will tailor make a skin treatment plan for you. They are all extremely knowledgeable and professional and use all the latest anti aging technologies and treatments. Amazing attention to detail from the beautiful space to the follow up care kits and check in emails from the therapists. Really a five star experience.

J Anastasopoulos

I have been with Dr Nerina Wilkinson and her team since 2021 and the level of professionalism is unmatched. So are the treatments, they truly have a solution for almost every skin or aesthetic concern. Could not love them more!

A Davids

My experience at Dr Nerina Wilkinson has been nothing but significant! I feel that for the first time, I understand my skin. Thanks to the lovely Louné, that has created a specific skin plan and routine for me. I am 39 years old and struggle with Pigmentation and Skin ageing. Our goal is to make my skin look as fresh, natural and glowing as possible. I have the utmost confidence in Louné to reach my goal. I started my journey with them in January 2023 and my results after doing a Meline Peel are already proofs that I am on the best plan. I am excited and confident to reach my goal and cannot wait for my next appointment! I would definitely recommend their professional opinions.

T Strauss

This is my honest review. I was very sceptical when I made an appointment at Dr Nerina Wilkinson and Associates, I thought like every other place that has influencers going there that it wouldn’t hold up to its reputation. I was wrong! Very wrong. Dr Cindy Kerbel was incredible, she took her time to explain not only my skin but all the available options for my skin. She has such a warm and kind energy. You immediately feel cared for. Honestly you won’t regret going here. I cannot wait for my next appointment. Thank you!

J Bentel

To avoid prolixity, you know your people are undeniably unbeatable when arguments relating to your age arise in conversations (read online dating apps). Despite clinging to the ‘wrong side’ of 30, I’ve made peace with those who assume I am still at varsity. Between Marisa and Bernice (with a shout-out to Natalie (as well as the rest of the team)) my skin and jawline (and the rest) have never looked more delicious. And when the Finance and Facility Manager is also a vibe, you know you’ve found a gem of a team! In short, I’m addicted (hypothetically, of course) to the needles (in a healthy wholesome way, naturally) and am never looking back (in particular at old Facebook photos when youth was allegedly in my favour). Thanks for keeping my aesthetic *ish together.

A Wright

I am so glad that, at the age of 30, I finally decided to come here! Such a warm and professional atmosphere, and Chantel made me feel so comfortable and excited for this journey. After my in-depth skin analysis and consultation, I was very happy with the first treatment, and for what has been planned ahead. Thank you!

F Badenhorst

I’ve gone for 2 appointments so far and 1. the service is incredible, such friendly and professional staff, 2. I had my skin analysed and then also went for a skin treatment and my skin is thanking me for it. I cannot wait to go back for more treatments. Highly recommend.

N Jacobs

I recently went to Dr Nerina Wilkinson + Associates to help me with my Rosacea. Walking into their beautiful, tranquil space is transforming alone. I love that they have a signature scent, which smells amazing. Each member of the team is passionate about what they do and incredibly knowledgeable, whilst always staying informed with the latest in skincare, technology etc.

B Georgiades

During my extended stay in Cape Town, I (Black American female), visited Dr. Nerina Wilkinson + Associates to maintain my skincare regimen while abroad. I was fortunate to work with my skincare specialist to develop a tailored skincare treatment. Not only did I receive great service, but she also provided detailed insight into the current state of my skin and offered additional recommendations for overall skin health. Chantel was excellent, demonstrating both kindness and informative expertise, and the facility was beautiful. And overall, I did see improvement in my skin’s texture and evenness, but I still have a ways to go.

C Okpara

Growing up I did not pay much attention to looking after my skin properly, but after starting my journey with Dr Nerina Wilkinson + Associates it has become one of the most important steps in my daily routine and I am loving it thanks to their delightful, informed and supportive team. I have always struggled with broken capillaries and dehydration, but have never known how to go about treating it and preventing further damage in the future. I had my first IPL session last week and I am absolutely shocked by the amazing results thus far. I was very wary about leaving my home during the COVID19 pandemic, but the team at Dr Nerina Wilkinson + Associates not only made me feel incredibly safe but I was also treated like a true queen during my session. After the treatment I received a ‘lucky packet’ of aftercare products and Bernice was there at my every beck and call (as I had many questions which were answered in such a timely and gracious manner). She also recommended products that have made my face feel softer and more youthful than ever before and I can already start seeing/feeling a difference. I am so grateful to the incredible team and I look forward to a future of beautiful care and loving myself in my own skin.

K Fourie

Growing up in the US, I went to dermatologist after dermatologist, and each one said the same three things: I have acne, it’s genetic, and it could be a lot worse. When I moved to Cape Town a few years ago, I heard from a friend that I needed to go see the women at the Nerina Wilkinson skin clinic, so I made an appointment – but I didn’t expect anything different. I left their office after my first appointment with Kim and I had some real hope for my skin to improve. She changed my home care, worked out a long term plan for me, and even gave me her personal cell number so I could message her if things weren’t working. It’s been over two years now and I have never been so happy with my skin. Kim and the other women at the skin clinic form the kindest and most caring team of professionals and I can’t thank them enough. From scalp PRP treatments for thinning hair, to lasers and peels for my rosacea, I’ve tried my fair share of treatments at this office and every single one of them has been worth it – I can honestly say these women have helped me feel like the best version of myself!

A Newell

“I have spent too much money over the past 10 years in hope to sort out my pigmentation and skin texture. Visited many (un)professionals and bought the most mediocre skincare. I heard about Dr Nerina via a friend. My last hope and the best decision I made. I was introduced to the Me Line peel and their skincare…this is now my go to as my skin has never looked this good and healthy ever. Extremely professional team, Bianca was my therapist. If you are looking for skin changing results and are serious about proper skincare, you should visit them. It’s worth all the money you will spend. An investment worth it…”


“Thank you to the wonderful ladies at your skin clinic. I have always suffered from problem skin. They have over the last few months advised me on the correct skincare and through their dedicated treatments I am now proud to show my skin without wearing too much makeup.”

Skincare Treatments

“Every day I look in the mirror, I can’t believe that this new skin in mine! I reached a point in my life where I thought that I would have to live with the consequences of the severe sun damage I have caused myself through years of surfing. Not only have you given me new skin Nerina, you have actually given me a new life.”

L.S, CO2 Laser Resurfacing Treatment

“My grateful thanks to you all for everything you do for me, and I mean that from the heart of my bottom!”

Skin Science Treatments

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