Mesobooster treatments are combination skin booster treatments aimed to bio-stimulate and rejuvenate all components of the skin (the epidermis, dermis, and hypodermis) in one session.

Mesoboosters in South Africa


Mesoboosters aim to counteract and delay signs signs of ageing, providing immediate aesthetic enhancement and sustained rejuvenation.

Mesoboosters offer a revolutionary approach to skincare, promoting cellular renewal and a natural glow, while deeply nourishing the skin to achieve a vibrant and youthful complexion.

What are Mesoboosters?

Mesobooster treatments are a blend of skin boosters designed to simultaneously bio-stimulate and rejuvenate all layers of the skin (epidermis, dermis, and hypodermis).

We utilise superior medical-grade ingredients, which include biomimetic peptides, essential vitamins, and minerals. These ingredients are combined with hyaluronic acid and gently introduced to the skin, aiming to stimulate and amplify the skin’s inherent production of collagen, elastin, and hyaluronic acid.

Learn about our approach, how Mesobooster treatments are performed and contact us to book a consultation.

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Frequently asked questions about Mesobooster treatments

What are skin boosters?

Skin boosters are specialised treatments designed to hydrate, rejuvenate, and enhance the skin’s texture, tone, and overall health. Comprising a series of micro-injections, skin boosters can deliver vital nutrients, vitamins, and hyaluronic acid deep into the layers of the skin. This process aims to improve skin elasticity, reduce fine lines, and provide a youthful glow. The aim of skin boosters is to provide non-surgical rejuvenation without undergoing more invasive procedures.

Our approach to a Mesobooster treatment

At Dr Nerina Wilkinson + Associates we understand the importance of skin health and embracing the facial structures and skin as a whole. The goal is to achieve harmonious results using facial reshaping injectables and state-of-the-art skin rejuvenating treatments.

No area of the face exists in isolation, all areas connected, therefore treating areas in isolation leads to exaggerated and aesthetically unattractive features.

By understanding how all areas of the face are interconnected and how treating one area communicates with another facial area, we are able to use much less product and produce constant and beautiful, natural results.

Start your Mesobooster journey! Contact us to book a consultation.

Who is the ideal candidate for Mesobooster treatments?

Mesobooster treatments are suitable for anyone with signs of ageing, who could benefit from improvements in skin tone, laxity, fine lines, and wrinkles.

It is an ideal boosting treatment to enhance or prolong the results from previous aesthetic treatments such as neurotoxin injections, dermal fillers, or bio-stimulators with CHA (calcium hydroxyapatite), or for those individuals wanting to achieve natural rejuvenation without drastic change.

How are Mesobooster treatments performed?

Before a Mesobooster treatment the skin is prepared with a selected skin peeling agent to prepare and optimize the skin surface and appearance.

This is followed by the insertion of a combination of medical grade active ingredients, selected depending on the underlying skincare concern, and are superficially injected into the skin either with a fine needle or cannula depending on the area and indication.

It is the combination of these two treatments that result in a holistic improvement in the quality and appearance of the skin.

Which areas can be treated with Mesobooster treatments?

While Mesoboosters provide excellent results in certain areas, they are not recommended for zones with a lot of movement or delicate skin.

Mesoboosters can be used to improve modest volume loss, skin laxity, and smooth fine lines in the following areas:

  • Forehead and templates
  • Mid-face 
  • Jawline 
  • Neck 
  • Back of the hands 

Mesoboosters are not suitable for delicate skin around the eyes, around the lips, deep nasolabial folds, around the mouth or in areas associated with constant movement.

What type of anaesthesia is used during Mesobooster treatments?

Your doctor will disinfect the injection site, then apply an anaesthetic (such as lidocaine to the area). The anaesthetic may be applied topically, injected, or may be included in the syringe.

What are the benefits of Mesobooster treatments?

Mesobooster treatments, enriched with a combination of skin boosters, offer a multi-faceted approach to skin enhancement. Here are the key benefits associated with Mesoboosters:

  • Instant improvement in complexion: Immediate improvement in skin texture and radiance post-treatment.
  • Collagen stimulation: Dive deeper to naturally amplify collagen, ensuring a tighter, youthful complexion over time.
  • Holistic rejuvenation: Active ingredients work both on the surface and underneath, promising overall skin health and vitality.
  • Resilience and elasticity: Each session fortifies the skin’s natural defences and elasticity, leading to lasting results.

For comprehensive skin rejuvenation in minimal time, Mesobooster treatments are the go-to solution.

How long does it take to see results from Mesobooster treatments?

After receiving a Mesobooster treatment, some immediate improvements might be noticeable, especially related to hydration and skin texture. However, the most significant results, driven by collagen stimulation, are usually evident after 6 weeks, with continued enhancement up to 3 months post-treatment. It’s a gradual process that ensures a natural and rejuvenated look.

How many Mesobooster treatments do you need to see results?

Typically, noticeable improvements can be seen after just one Mesobooster treatment. However, for optimal results, and depending on the indication, treatments may need to be repeated 3-5 times over a weekly, monthly, or three-monthly period. The exact number can vary based on individual skin needs and desired outcomes.

How often should I have a Mesobooster treatment?

For optimal results and depending on the severity of concerns, a patient may required multiple Mesobooster treatments over a set period of a few weeks or months.

A follow-up appointment is required 12 weeks after your treatment to assess results.

Maintenance treatments to sustain long-term results may completed within 6-12 weeks after initial sessions.

Always consult with an aesthetic doctor to personalise your treatment plan.

How long does it take to perform a Mesobooster treatment?

Treatment time can vary between 30 – 45 minutes, depending on the area(s) treated.

What is the recovery time for a Mesobooster treatment?

There is no downtime after a Mesobooster treatment and you can immediately return to regular activities right away.

How much does a Mesobooster treatment cost?

The cost of a Mesobooster treatment is determined by factors like your facial structure, specific concerns, individual objectives, the amount of product needed, and the exact course of treatment.

An accurate estimate will be provided following your first consultation with our Aesthetic Doctors. To book your skincare consultation, contact us today.

Are there alternative treatments for Mesobooster treatments?

Certainly, there are other treatments available that target facial skin ageing and aim to refine the skin’s structure.

Natural-Lift™: This innovative signature treatment offers a non-invasive approach to refresh and rejuvenate the face, enhancing its natural contours.

Bio skin remodelling: This injectable treatment provides improved skin quality and texture, utilising soft filler to elevate facial features and a skin booster to stimulate skin enhancement over time. 

Biostimulators: These injections utilise Calcium Hydroxyapatite (CaHA) and Poly-L-Lactic Acid (PLLA) to stimulate collagen production beneath the skin, promoting firmness and rejuvenation in specific areas like the face, neck, décolleté, and hands.

Muscle relaxing injections: Designed to relax dynamic facial muscles, botulinum toxin injections provide patients with a youthful and rejuvenation appearance by softening fine lines and wrinkles.

What are the possible risks, side effects and complications associated with Mesobooster treatments?

Administered in a sterile medical setting by a seasoned specialist, the risks associated with Mesobooster treatments can be reduce considerably

Like other injectables, Mesoboosters are associated with their own set of potential side effects.

Common reactions post-treatment can include redness, swelling, tenderness, pain, and itching. These are typically mild and usually subside within 24 – 48 hours. Bruising and swelling may persist up to a week, but employing ice packs or cold compresses for 24 hours post-treatment can mitigate these effects.

Some individuals might also discern small lumps under the skin in treated areas. If detected, it’s recommended to massage these areas gently. Persistent lumps beyond 5 days should be communicated to your medical practitioner.

For a comprehensive understanding of potential side effects and to address any concerns related to Mesobooster treatments, kindly contact us.

Mesobooster treatments: Before and After



  • We advise strongly that you avoid alcohol, garlic, fish oil supplements, aspirin, or any other anti-inflammatory drugs for pain, swelling, and/or fever, such as medicine containing diclofenac, mefenamic acid, indomethacin, or ibuprofen. Ask your doctor or pharmacist whether your medication includes any of these ingredients. This will reduce the risk of bruising or bleeding at the point of injection.
  • Because bruising and swelling are the most common side effects, especially in the lower face, schedule appointments at least 48 hours before any significant event.
  • Please let us know if you have been to the dentist / oral hygienist or are planning to go to the dentist/ hygienist in the next 4 weeks.
  • If this is your first visit you will need to provide us with information regarding your medical history and any medical concerns, as well as details of any allergies you have or medications you are taking.


Please note that you will have to arrive without makeup to prevent any Biofilm (bacterial infections) when doing any filler or bio-stimulator treatments.

Once the Doctor has determined and confirmed your areas of concern by means of a detailed consultation, they will proceed. It is important that you’re honest with the doctor about your medical history, medication, and expectations during this time. So that, if they are not in line with the treatment, then another can be recommended instead.


Please follow these instructions carefully to aid in achieving optimal results:

For 2 hours: Avoid make-up at the injection site to avoid contamination in the area.

For 12 hours: Massage the treated areas if you feel any small bumps

For 24 hours: Avoid any high-intensity exercise or activities, exposure to sunlight, tanning beds, or extreme weather conditions

For 24 hours: Apply an ice pack or cold compresses to the treated areas as with most injectable treatments there may be some redness, swelling, and irritation.

For 2 weeks: Avoid dental procedures and any invasive skin treatments

For 2 weeks: Avoid any other injectable treatments, such as dermal fillers.

Please follow these instructions carefully to aid in achieving optimal results: Please note that no treatment can halt the ageing process completely, you will require top-up treatments if you want to maintain the effect, so please ask your doctor when she would recommend scheduling another appointment.

Where are Mesobooster treatments performed in Cape Town?

Mesobooster treatments are typically administered in select private cosmetic clinics, especially those specialising in advanced skin science treatments.

Dr Nerina Wilkinson + Associates proudly offers these treatments at their upscale and exclusive clinic nestled in the iconic V&A Waterfront. Dr. Nerina Wilkinson is the pioneer behind our premier medical aesthetics clinic delivering unparalleled aesthetic expertise with a team of specialists. 

Dive deeper into our aesthetic couture journey or contact us.

What makes Mesoboosters different from dermal fillers?

Mesoboosters are not fillers or volumizers per se and offer lasting collagen production by stimulating your fibroblasts to form collagen as well as improving the appearance and condition of the superficial layers of the skin.

These treatments should be considered where subtle improvement in the appearance is warranted, or, as a booster treatment to a dermal filler.


Similar to a Mesobooster treatment


N-LIFT® precisely places very small volumes of Hyaluronic Acid filler in multiple areas to build deep structural support and shift the balance between the elevator and depressor muscles of the face.
View Treatment

Bio Skin Remodelling

Bio skin remodelling is an injectable anti-ageing treatment that provides the combined benefits of a subtle lift from an ordinary soft filler along with the skin quality enhancing effects of a skin booster.
View Treatment

Muscle Relaxing Injections

Botulinum toxin treatments (Neuromodulators) are popular non-surgical procedures that appeal to adults looking to attain a more youthful and relaxed appearance, and also to younger clients who want to prevent the formation of fine lines and wrinkles.
View Treatment


Biostimulators are biologically active substances that can be injected under the skin to improve the quality and functioning of the skin and substructures to firm, rejuvenate and improve the aesthetic appearance.
View Treatment


Mesotherapy is a popular, minimally invasive technique that uses small injections to introduce active ingredients into the superficial layers of the skin in order to stimulate, feed and regenerate the skin without damage or trauma.
View Treatment


The Skin Science Team

About Dr Nerina Wilkinson + Associates

At Dr Nerina Wilkinson + Associates, our primary goal is providing an excellent patient experience from start to finish. Whether you’re exploring skincare treatment options, evaluating an aesthetic medical procedure, or considering cosmetic surgery, our team stands by your side, guiding and supporting you throughout your journey.

Skin Science & Aesthetic Couture

Our all-female team deeply understands the importance of naturally radiant skin. As pioneers in the skincare industry, we’ve introduced groundbreaking rejuvenation methods, including our signature skincare treatments such as 3D Medical Skin Needling, FORMA™ Hydralyft , and the Dr. Vampire Facial.

Our Patients'


“I have spent too much money over the past 10 years in hope to sort out my pigmentation and skin texture. Visited many (un)professionals and bought the most mediocre skincare. I heard about Dr Nerina via a friend. My last hope and the best decision I made. I was introduced to the Me Line peel and their skincare…this is now my go to as my skin has never looked this good and healthy ever. Extremely professional team, Bianca was my therapist. If you are looking for skin changing results and are serious about proper skincare, you should visit them. It’s worth all the money you will spend. An investment worth it…”


“Thank you to the wonderful ladies at your skin clinic. I have always suffered from problem skin. They have over the last few months advised me on the correct skincare and through their dedicated treatments I am now proud to show my skin without wearing too much makeup.”

Skincare Treatments

“Every day I look in the mirror, I can’t believe that this new skin in mine! I reached a point in my life where I thought that I would have to live with the consequences of the severe sun damage I have caused myself through years of surfing. Not only have you given me new skin Nerina, you have actually given me a new life.”

L.S, CO2 Laser Resurfacing Treatment

Start your

Mesobooster treatment journey

At our premier skin clinic and plastic surgery practice situated in the V&A Waterfront, Cape Town, our dedicated team of skincare specialists is poised to guide you through every stage of your treatment journey.

With unparalleled expertise and enthusiasm, we guarantee tailored Mesobooster treatments to unveil revitalised and radiant skin.

Contact us today and take the first step on your treatment journey.